대한핵의학회:학술대회논문집

대한핵의학회 (The Korean Society of Nuclear Medicine)
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Rhenium-188 생산

Production of Re-188

  • 양승대 (원자력병원 싸이클로트론 응용연구실) ;
  • 서용섭 (원자력병원 싸이클로트론 응용연구실) ;
  • 김상욱 (원자력병원 싸이클로트론 응용연구실) ;
  • 임상무 (원자력병원 싸이클로트론 응용연구실)
  • Yang, Seung-Dae (Laboratory of Cyclotron Application, Korea Cancer Center Hospital) ;
  • Suh, Yong-Sup (Laboratory of Cyclotron Application, Korea Cancer Center Hospital) ;
  • Kim, Sang-Uk (Laboratory of Cyclotron Application, Korea Cancer Center Hospital) ;
  • Lim, Sang-Moo (Laboratory of Cyclotron Application, Korea Cancer Center Hospital)
  • 발행 : 1999.05.21
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초록

$^{188}Re$ (${\beta}^-=2.2$ MeV; ${\gamma}^-$=155 keV; $T_{1/2}$=16.9 hours) is an attractive therapeutic radioisotope which is produced from decay of reactor-produced tungsten-188 parent ($T_{1/2}$=69 days). $^{188}W$ has been produced from the double neutron capture reaction of $^{186}W.\;^{188}Re$ can be easily obtained by elution of saline on alumina based $^{188}W/^{188}Re$ generator, which is commercially available. Complexes labelled with $^{188}Re$ have been developed for the radiotherapy treatment of diseases because of the desirable nuclear properties of the radioisotope and it's chemical properties similar to those of technetium, a well established diagnostic agent.

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