Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
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Chlorpromazine Inhibits Store-operated Calcium Entry and Subsequent Norepinephrine Secretion in PC12 Cells

  • Park, Se-Young (Department of Life Science, Pohang University of Science and Technology) ;
  • Kim, Yong-Hyun (Department of Life Science, Pohang University of Science and Technology) ;
  • Lee, Yong-Kyu (Department of Food Engineering, Dongseo University) ;
  • Kim, Kyong-Tai (Department of Life Science, Pohang University of Science and Technology)
  • Published : 1999.06.01
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Abstract

The effect of chlorpromazine on the store-operated Ca$\^$2＋/ entry subsequently activated via the phospholipase C signaling pathway was investigated in PC12 cells. Chlorpromazine caused a rapid decline of the bradykinin-induced Ca$\^$2＋/ increase to basal level without attenuating the peak level.(omitted)

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