Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
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Protein Kinase Modulates the $GABA_c$ Currents in Cone-horizontal Cell Axon-terminals Isolated from Catfish Retina

  • Paik, Sun-Sook (Department of Physics and Biophysics, College of Medicine, The Catholic University of Korea) ;
  • Lee, Sung-Jong (Department of Physics and Biophysics, College of Medicine, The Catholic University of Kore) ;
  • Jung, Chang-Sub (Department of Physics and Biophysics, College of Medicine, The Catholic University of Kore) ;
  • Bai, Sun-Ho (Department of Physics and Biophysics, College of Medicine, The Catholic University of Korea)
  • Published : 1999.06.01
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Abstract

Protein kinase modulation of gamma-aminobutyric acid C (GABA$_{c}$) currents in freshly dissociated catfish retinal cone-horizontal cell axon-terminals was studied under voltage clamp with the use of the whole cell patch-clamp technique. Responses to pulses of GABA were monitored in intracellular application of adenosin 3',5'-cycle monophophate (cAMP)-dependent protein kinase (PKA) and protein kinase C (PKC) activators, and their inhibitors or inactive analogues.(omitted)d)

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