Biophysical Characteristics of $Mg^{2+}$ Blockades in Ion Channels and Their Physiological Roles

  • Park, Chul-Seung (Department of Life Science, Kwangju Institute of Science and Technology (K-JIST))
  • Published : 1999.06.01

Abstract

Ionic currents through many different cation channels are specifically reduced by internal and/or external $Mg^{2+}$ within a concentration range of physiological relevance. Although there are many ways for a divalent cation to reduce channel currents, the current blockade by directly binding to a conduction pore has been most well studied.(omitted)

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