Insights into Eukaryotic Multistep Phosphore lay Signal Transduction Revealed by the Crystal Structure of Ypd1p from Saccharomyces cerevisiae

  • Song, Hyun-Kyu (Department of Chemistry, College of Natural Sciences, Seoul National University) ;
  • Lee, Jae-Young (Department of Chemistry, College of Natural Sciences, Seoul National University) ;
  • Lee, Myong-Gyong (Department of Chemistry, College of Natural Sciences, Seoul National University) ;
  • Jinho Moon (Department of Chemistry, College of Natural Sciences, Seoul National University) ;
  • Kyeongsik Min (Department of Chemistry, College of Natural Sciences, Seoul National University) ;
  • Yang, Jin-Kuk (Department of Chemistry, College of Natural Sciences, Seoul National University) ;
  • Suh, Se-Won (Department of Chemistry, College of Natural Sciences, Seoul National University)
  • Published : 1999.06.01

Abstract

"Two-component" phosphorelay signal transduction systems constitute a potential target for antibacterial and antifungal agents, since they are found exclusively in prokaryotes and lower eukaryotes (yeast, fungi, slime mold, and plants) but not in mammalian organisms.(omitted)

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