Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
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Block of HERG Channels Expressed in Xenopus Oocytes by External $H^+$

  • Jo, Su-Hyun (Department of Life Science, Pohang University of Science and Technology) ;
  • Kim, Injune (Department of Life Science, Pohang University of Science and Technolog) ;
  • Yung E. Earm (Department of Physiology, Seoul National University College of Medicin) ;
  • Lee, Chin-Ok (Department of Life Science, Pohang University of Science and Technolog) ;
  • Ho, Won-Kyung (Department of Physiology, Seoul National University College of Medicine)
  • Published : 1998.06.01
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Abstract

We reported previously that HERG current, molecular equivalent of I$_{kr}$, expressed in Xenopus oocytes is blocked by external $Ca^{2＋}$ and $Mg^{2＋}$. In the present study, we have investigated the effect of external H＋ on HERG current (I$_{HERG}$) using the two microelectrode voltage clamp.(omitted)ted)

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