Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
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Role of Phospholipase C-delta1 in the Bradykinin Receptor-Mediated Signaling in PC 12 cells

  • Kim, Yong-Hyun (Dept of Life Science, Pohang University of Science and Technology) ;
  • Kim, Kyong-Tai (Dept of Life Science, Pohang University of Science and Technology)
  • Published : 1998.06.01
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Abstract

The role of a phosphoinositide-specific phospholipase C, PLC-deltal, in the bradykinin receptor-mediated signaling pathway was investigated using a clone of stably overexpressed PLC-deltal in rat pheochromocytoma (PC12) cells. Stimulation with bradykinin induced significantly higher [Ca$\^$2＋/]i rise in PLC-deltal-overexpressed cells (PC12-D1) than in the wild type (PC12-W) and the vector-transfected (PC12-V) cells.(omitted)

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