Membrane Topology of the Integral Membrane Transporter for Ribose

  • Published : 1998.06.01

Abstract

RbsC of Escherichia coli is the integral membrane component of the high-affinity ribose transport system classified as the AraH family. To understand the function and structure of RbsC, the topology of RbsC was investigated by alkaline phosphatase fusion. Characterization of a total of 64 RbsC-PhoA fusions revealed that RbsC is composed of six transmembrane helixes and has three periplasmic and two cytoplasmic loops.(omitted)

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