NMR and Molecular Modeling Studies on the Structures of AA Mismatched DNA Oligomers

  • Lee, Chulhyun (Magnetic Resonance Group, Korea Basic Science Institute) ;
  • Chaejoon Cheong (Magnetic Resonance Group, Korea Basic Science Institut) ;
  • Lee, Jo-Woong (Dept of Chemistry, Seoul National University)
  • Published : 1998.06.01

Abstract

Since the repair efficiency of non-Watson-Crick base pairs in DNA is affected by the mismatched base-pairs and their neighbor sequences, the structural studies are necessary for the elucidation of the repair efficiency. NMR and molecular modeling studies on the DNA duplexes including AA mismatches were performed.(omitted)

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