Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)
- 1998.06a
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- Pages.14-14
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- 1998
Zinc-induced Neurotoxicity and Its Role in Brain Diseases
- Koh, Jae-Young (Department of Neurology and the CNS Zinc Study Group, University of Ulsan College of Medicine)
- Published : 1998.06.01
Abstract
Mammalian brian contains substantial amounts of chelatable zinc in presynaptic vesicles of certain glutamatergic terminals. The synaptic zinc is released with intense neuronal activity, suggesting its role in synaptic transmission. However, in pathological conditions, zinc may get released too excessively, which may contribute to neuronal death as shown in cortical cultures.(omitted)
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