Proceedings of the Korean Society of Applied Pharmacology (한국응용약물학회:학술대회논문집)

The Korean Society of Applied Pharmacology (한국응용약물학회)
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Novel Antioxidants, Stc-l and Stc-2, from Stereum ostrea

  • Kim, Young-Hee (Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ;
  • Yun, Bong-Sik (Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ;
  • Kim, Jong-Pyong (Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ;
  • Moon, Suk-Sik (Department of Chemistry, Kongju National University) ;
  • Yoo, Ick-Dong (Korea Research Institute of Bioscience and Biotechnology (KRIBB))
  • Published : 1998.11.01
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Abstract

In the course of screening for new natural compounds having antioxidant activity from microbials, mushrooms as well as plants. We have isolated novel sesquiterpenoid and officinalic acid from methanolic extracts of Stereum ostrea. The dried fruit body( 450 g) of Stereum ostrea was extracted with methanol, then methanolic extract was partitioned between water and hexane, chloroform, and ethyl acetate, subsequently. The chloroform extract was subjected on silica gel, Sephadex LH-20 and RP-18 column chromatography, successively. And two compounds were isolated and identified as new triterpenoids and officinalic acid using $^1$H - NMR, $\^$13/C - NMR as well as Mass spectra.

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