한국독성학회:학술대회논문집 (Proceedings of the Korean Society of Toxicology Conference)
- 한국독성학회 1998년도 국제심포지움 및 추계학술대회
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- Pages.36-36
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- 1998
Tumorigenicity of benzo(a)pyrene and benzo(a)pyrene diol epoxides in v-Ha-ras transgenic TG-AC mice
- 이병무 (성균관대 약대) ;
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- Lee Byung Mu (Division of Toxicology, College of Pharmacy, Sungkyunkwan University) ;
- Germolec Dori (National Institute of Environmental Health Sciences, Lab. of Immunology(D.G.), Lab, of Pharmmacology(K.H.J), Lab. of Environmental Carcinogenesis and Mutagenesis,(R.W.T)) ;
- Jeohn Kwang-Ho (National Institute of Environmental Health Sciences, Lab. of Immunology(D.G.), Lab, of Pharmmacology(K.H.J), Lab. of Environmental Carcinogenesis and Mutagenesis,(R.W.T)) ;
- Tennant Raymond W, (National Institute of Environmental Health Sciences, Lab. of Immunology(D.G.), Lab, of Pharmmacology(K.H.J), Lab. of Environmental Carcinogenesis and Mutagenesis,(R.W.T))
- 발행 : 1998.10.01
초록
Tumorigenicity of benzo(a)pyrene (BP) and benzo(a)pyrene diol epoxides ((+)BPDE-1, (-)BPDE-1) was investigated in transgenic TG-AC mice carrying v-Ha-ras oncogene fused to the promoter of the mouse embryonic a-like, z-globin gene. Animals were topically treated twice per week for 25weeks with BPDE (10
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