대한의용생체공학회:학술대회논문집 (Proceedings of the KOSOMBE Conference)
- 대한의용생체공학회 1997년도 춘계학술대회
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- Pages.92-94
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- 1997
Statistical Analysis of rCBF Positron Emission Tomography Images for the Functional Mapping of Human Memory
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이재성
(서울대학교 대학원 협동과정 의용생체공학) ;
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이동수
(서울대학교 의과대학 핵의학교실) ;
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박광석
(서울대학교 의과대학 의공학교실) ;
- 곽철은 (서울대학교 의과대학 핵의학교실) ;
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이상건
(서울대학교 의과대학 신경과학교실) ;
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정준기
(서울대학교 의과대학 핵의학교실) ;
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이명철
(서울대학교 의과대학 핵의학교실) ;
- 고창순 (서울대학교 의과대학 핵의학교실)
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Lee, J.S.
(Interdisciplinary Program in Medical and Biological Engineering Major, Seoul National University) ;
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Lee, D.S.
(Department of Nuclear Medicine, Seoul National University) ;
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Park, K.S.
(Department of Biomedical Engineering, Seoul National University) ;
- Kwark, C. (Department of Nuclear Medicine, Seoul National University) ;
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Lee, S.K.
(Department of Neurology, Seoul National University) ;
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Chung, J.K.
(Department of Nuclear Medicine, Seoul National University) ;
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Lee, M.C.
(Department of Nuclear Medicine, Seoul National University) ;
- Koh, C.S. (Department of Nuclear Medicine, Seoul National University)
- 발행 : 1997.05.23
초록
By measuring the increase of regional cerebral blood flow (rCBF) during the activation tasks, we can describe the brain regions that participate in certain specific functions. In this study, we composed the functional maps of verbal and nonverbal memory by performing the rCBF positron emission tomography (PET) activation studies and analyzing the differences between control and each activation state. Successive four tasks, which consist of one control state and three different activation tasks, were performed on 6 normal volunteers. All images were spatially normalized on standard atlas and the differences between control and activation states were statistically analyzed. The verbal memory activated predominantly left-sided structures, especially left superior temporal cortex, and the nonverbal short-term memory activated the right frontal cortex. Also, some regions ,where is thought to be related with short-term memory system, such as cingulate gyrus and hippocampus were activated. We conclude that biological validity of the brain regions for verbal and nonverbal memory could be tested using rCBF PET imaging technique and statistical analysis.
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