Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
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Structural and Functional Study of Antimicrobial Peptide Using NMR Spectroscopy

  • Suh, Jeong-Yong (Department of Chemistry, Korea Advanced Institute of Science and Technology) ;
  • Lee, Young-Tae (Department of Chemistry, Korea Advanced Institute of Science and Technolog) ;
  • Park, Byong-Seok (Department of Chemistry, Korea Advanced Institute of Science and Technology)
  • Published : 1997.07.01
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Abstract

Structure of potent derivatives of gaegurin, an antimicrobial peptide from Korean frog, is studied by CD and NMR spectroscopy. Gaegurin did not show any secondary structure in aqueous environment, but adopted ${\alpha}$-helix in aqueous TFE solution, SDS and liposome buffer. NMR study showed distinct difference in stability near proline residue in helix.(omitted)

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