Quantitative Assessment of Cerebral Perfusion Reserves Using Normalized Difference Ratio Image of Brain SPECT

뇌혈류 SPECT에서 정규화감산영상을 이용한 뇌혈류비축능의 정량적 평가에 관한 연구

  • Lee, J.S. (Interdisciplinary Program in Medical and Biological Engineering Major) ;
  • Kwark, C. (Department of Nuclear Medicine, Seoul National University) ;
  • Park, K.S. (Department of Biomedical Engineering, Seoul National University) ;
  • Jeong, J.M. (Department of Nuclear Medicine, Seoul National University) ;
  • Lee, D.S. (Department of Nuclear Medicine, Seoul National University) ;
  • Chung, J.K. (Department of Nuclear Medicine, Seoul National University) ;
  • Lee, M.C. (Department of Nuclear Medicine, Seoul National University) ;
  • Koh, C.S. (Department of Nuclear Medicine, Seoul National University)
  • 이재성 (서울대학교 대학원 협동과정 의용생체공학) ;
  • 곽철은 (서울대학교병원 핵의학과) ;
  • 박광석 (서울대학교 의과대학 의공학교실) ;
  • 정재민 (서울대학교병원 핵의학과) ;
  • 이동수 (서울대학교병원 핵의학과) ;
  • 정준기 (서울대학교병원 핵의학과) ;
  • 이명철 (서울대학교병원 핵의학과) ;
  • 고창순 (서울대학교병원 핵의학과)
  • Published : 1996.05.17

Abstract

Sequential brain SPECT imaging has been used to assess the cerebral perfusion reserve(CPR) in cerebrovascular diseases(CVD). We have realized a parametric images of CPR using normalized difference ratio and deadtime correction. For the anatomical localization of CPR, the parametric images were registered to the contours of the cerebral regions using optimal threshold method. The parametric imags reflected the CPR more reliably and distinctively. We conclude that the qunatitative estimation of CPR using normalized difference ratio image could be useful for the diagnosis and assessment of postoperative prognosis in CVD.

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