Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
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Both $^{45}Ca^{2+}$ Uptake and $^{45}Ca^{2+}$ Release were Decreased in the Junctional Sarcoplasmic Reticulum Vesicles of Diabetic Heart

  • Kim, Won-Tae (Dept. of Agric. Chem., Chungbuk Nat′l University) ;
  • Cho, Kwang-Hyun (Dept. of Agric. Chem., Chungbuk Nat′l University) ;
  • Kim, Hae-Won (Dept. of Pharmacol. University of Ulsan Coll. of Medicin) ;
  • Kim, Young-Kee (Dept. of Agric. Chem., Chungbuk Nat′l University)
  • Published : 1996.07.01
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Abstract

Abnormally high $Ca^{2+}$ concentrations have been reported in the cardiac myocytes of diabetic mellitus (DM). In order to elucidate the molecular mechanisms of the intracellular $Ca^{2+}$ overload, the activities of $^{45}$ Ca$^{2+}$ uptake and $^{45}$ Ca$^{2+}$ release were measured from the vesicles of junctional SR (Heavy SR, HSR). (omitted)omitted)

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