The Molecular Mechanical Model of DD-Peptidase

  • Lim, Eongjin (Department of Chemistry, Hanyang University) ;
  • Won, Youngdo (Department of Chemistry, Hanyang University)
  • 발행 : 1996.07.01

초록

In order to establish the structural requirements for designing new ${\beta}$-lactam antibiotics it is necessary to build the molecular model of a penicillin binding protein. D-alanyl-D-alanine carboxypeptidase/transpeptidase (DD-peptidase) is a good model for PBPs. The X -ray crystallographic structure of DD-peptidase has been reported at the 1.6${\AA}$ resolution. (omitted)

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