Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)
- 1996.07a
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- Pages.19-19
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- 1996
Nuclear Magnetic Resonance Study on the CRP and CRP*RNA polymerase complex
- Lee, Tae-Woo (College of Pharmacy, Seoul National University) ;
- Park, Sang-Ho (College of Pharmacy, Seoul National University) ;
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Lee, Bong-Jin
(College of Pharmacy, Seoul National University)
- Published : 1996.07.01
Abstract
Cyclic AMP receptor protein (CRP) from E. Coli plays a key role in regulation of the expression of more than 20 genes of the bacterium. CRP binds in the presence of cAMP to a specific target site near the promoter of each gene under its regulation. CRP is a dimer (Mr～47,000) of two identical subunits. There are two binding domains in the CRP monomer, one for the binding of the cAMP and the other for the binding of specific DNA sequences. (omitted)
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