한국응용약물학회:학술대회논문집 (Proceedings of the Korean Society of Applied Pharmacology)

한국응용약물학회 (The Korean Society of Applied Pharmacology)
권호 표지

Acute oral and subcutaneous toxicity of Aloewhite in Mice

  • Kim, Hyung-Sik (Division of Toxicology, School of Pharmacy, Sung Kyun Kwan University) ;
  • Ahn, Mi-Young (Division of Toxicology, School of Pharmacy, Sung Kyun Kwan University) ;
  • Kwack, Seung-Jun (Division of Toxicology, School of Pharmacy, Sung Kyun Kwan University) ;
  • Kim, Kyu-Bong (Division of Toxicology, School of Pharmacy, Sung Kyun Kwan University) ;
  • Lee, Seung-Ki (Division of Toxicology, School of Pharmacy, Sung Kyun Kwan University) ;
  • Chun, Sun-Ah (Division of Toxicology, School of Pharmacy, Sung Kyun Kwan University) ;
  • Lim, So-Young (Division of Toxicology, School of Pharmacy, Sung Kyun Kwan University) ;
  • Park, Hyun-Sun (Division of Toxicology, School of Pharmacy, Sung Kyun Kwan University) ;
  • Hong, Che-Young (Division of Toxicology, School of Pharmacy, Sung Kyun Kwan University)
  • 발행 : 1996.04.01
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초록

-Acute oral and subcutaneous toxicity of Aloewhite(30% aloesine) were carried out in ICR mice. In this study, we daily examined number of deaths, clinical signs, body weights, and pathological examinations for 14 days after single oral and subcutaneous administration of Aloewhite with different dose levels. Aloewhite did not show any remarkable toxic effect in mice. These results suggest that oral and subcutaneous LD$\sub$50/ values in mice were over 6.8g/kg and 10g/kg, respectively.

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