한국응용약물학회:학술대회논문집 (Proceedings of the Korean Society of Applied Pharmacology)
- 한국응용약물학회 1995년도 춘계학술대회
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- Pages.80-80
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- 1995
NMR study of the interaction of T4 Endonuclease V with DNA
- Lee, Bong-Jin (Coll. of Pharmacy, Seoul National University) ;
- Im, Hoo-Kang (Coll. of Pharmacy, Seoul National University) ;
- Hyungmi Lihm (Coll. of Pharmacy, Seoul National University) ;
- Yu, Jun-Suk (Coll. of Pharmacy, Seoul National University)
- 발행 : 1995.04.01
초록
T4 Endonuclease V (Mw 16,000) acts as a repair enzyme for UV induced pyrimidine dimers in DNA. Many researchers have studied the biochemical characteristics of the enzyme. However the precise action mechanism of T4 endo V has not fully elucidated yet. In our laboratory NMR spectroscopy technique is being used for the structural study of T4 endo V. Because of its low temperature stability and high content of
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