On the Detection of Parameter Changes in Dynamical Systems for an Early Diagnosis of Cancer

암의 조기진단을 위한 계수변화 검출에 관한 연구

An early detection of cancer is very important for the complete cure of cancer. Therefore, it is considered a diagnosis of cancer via the detection of an abrupt change from the healthy state to the cancerous state. It includes the development of algorithm for the detection of parameter change for conditionally-linear stochastic systems for the cancer diagnosis. The statistical testing is proposed to implement a parameter change algorithm. The detection algorithm studied in this research is based on sequential hypotheses testing in a so-called local asymptotic framework. Here a simple numerical example is provided to highlight some of the concepts and to provide a basis for further investigation. Despite its simplicity this research may have practical application in clinical oncology.