대한예방의학회:학술대회논문집

The Korean Society for Preventive Medicine (대한예방의학회)
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Recruitment for Phase I of the Trials of Hypertension Prevention

  • Satterfield Suzanne (Department of Medicine, Brigham and Women's Hospital and Harvard Medical School) ;
  • Borhani Nemat O. (School of Medicine, University of Nevada) ;
  • Whelton Paul (Welch Center for Prevention, Epidemiology and Clinical research, The Johns Hopkins University School of Hygiene & Public Health and School of Medicine) ;
  • Goodwin Laretha (Department of Preventive Medicine, University of Tenessee) ;
  • Brinkmann Connie (Louis University School of Medicine) ;
  • Charleston Jeanne (Welch Center for Prevention, Epidemiology and Clinical research, The Johns Hopkins University School of Hygiene & Public Health and School of Medicine) ;
  • Corkery Beth Walker (East Boston Neighborhood Health Center) ;
  • Dolan Lee (New Jersey Medical School) ;
  • Hataway Heidi (Division of General and Preventive Medicine, University of Alabama at Brimingham) ;
  • Hertert Stephanie (Kaiser Permanente Center for Health Research) ;
  • Lakatos Ed (Division of Epidemiology and Clinical Applicatons, National Heart, Lung, and Blood Institute) ;
  • Milas N. Carole (Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh) ;
  • Morris Martha Clare (East Boston Neighborhood Health Center)
  • Published : 1994.02.01
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Abstract

Phase I of the Trials of Hypertension Prevention was a multicenter, randomized, controlled trial designed to determine the efficacy of seven nonpharmacologic interventions in reducing blood pressure among persons with high-normal diastolic blood pressure. the initial goal for recruitment was to enroll 2,100 participants over a nine-month period. The yield from the first screening visit to randomization was 13% overall, with clinic-specific yields ranging from 4.5% to 31.7%. After five months of recruitment, approximately 60% of the goal for that point in the recruitment timetable had been randomized. Clinical centers falling short of their goals at that time altered their recruitment strategies and intensified their efforts, and centers that had exceeded their goals recruited additional participants. As a result, 2,182 participants, or 104\% of the goal for recruitment, were randomized over a 13-month period. Those clinics using a cohort, or wave, type of enrollment were most successful in achieving their recruitment goals within the prescribed timetable.

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