한국응용약물학회:학술대회논문집 (Proceedings of the Korean Society of Applied Pharmacology)
- 한국응용약물학회 1994년도 춘계학술대회 and 제3회 신약개발 연구발표회
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- Pages.243-243
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- 1994
Inhibitory effects of Cortex Mori on Compound 48/80-induced Anaphylactic Shock and Cutaneous Reaction
- Jun, Byoung-Deuk (Chonbuk National University Medical School) ;
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Chai, Ok-Hee
(Chonbuk National University Medical School) ;
- Park, Myoung-Hee- (Chonbuk National University Medical School) ;
- Lee, Hern-Ku- (Department of Anatomy and Microbiology) ;
- Lee, Moo-Sam- (Chonbuk National University Medical School)
- 발행 : 1994.04.01
초록
Although active systemic anaphylaxis and passive cutaneous anaphylaxis have been empolyed to study anaphylactic hypersensitivity, it is difficult and time-consuming to induce these reactions in experimental animals. In recent, Jun et al have found a simple method to induced anaphylactic hypersensitivity such as anaphylactic shock(AS) and cutaneous reaction(CR) using compound48/80. Cortex mori (Morus alba L.), the root bark of mulberry tree has been used as an antiphlogistic, diuretic, and expectorant in herbal medicine. The purpose of this study was to determine whether the methanol extract of Cortex mori could inhibit the compound 48/80-induced AS and CR. To induce AS, various doses of compound 48/80 (5, 7.5, 10, 15
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