Proceedings of the Ginseng society Conference (고려인삼학회:학술대회논문집)
- 1993.09a
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- Pages.127-131
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- 1993
DIFFERENTIATION MECHANISM OF GINSENOSIDES IN CULTURED MURINE F9 TERATOCARCINOMA STEM CELLS
- Lee H.Y. (Department of Molecular Biology, Pusan National University, the Cancer Research Center) ;
- Kim S.I. (Korea Ginseng and Tobacco Research Institute) ;
- Lee S.K. (College of Pharmacy and the Research Center for New Drug Development, Seoul National University) ;
- Chung H.Y. (Department of Phamacy, Pusan National University) ;
- Kim K.W. (Department of Molecular Biology, Pusan National University, the Cancer Research Center)
- Published : 1993.09.01
Abstract
The effects of total ginseng saponin. extracts of Panax ginseng C.A. Meyer, on the differentiation of F9 teratocarcinoma stem cells were studied. F9 stem cells cultured in the presence of ginseng saponin together with dibutyric cAMP became parietal endoderm - like cells. Moreover, the expressions of differentiation marker genes. laminin. type IV collagen. and retinoic acid
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