Susceptibility Contrast Enhancement Imaging in MRI

핵자기 공명 단층 촬영에서의 자화율 강조 영상법

  • Ro, Y.M. (Dept. of Electrical Science, Korea Advanced Institute of Science and Technology) ;
  • Mun, C.W. (Asan Institute for Life Sciences, NMR Lab.) ;
  • Lim, T.H. (Asan Institute for Life Sciences, NMR Lab.) ;
  • Cho, Z.H. (Dept. of Electrical Science, Korea Advanced Institute of Science and Technology)
  • 노용만 (한국과학기술원 전기 및 전자 공학과) ;
  • 문치웅 (아산 생명 과학 연구소, NMR 연구실) ;
  • 임태환 (아산 생명 과학 연구소, NMR 연구실) ;
  • 조장희 (한국과학기술원 전기 및 전자 공학과)
  • Published : 1992.05.15

Abstract

In MRI, an image contrast can be developed as a result of the susceptibility effect if an object has paramagnetic substances. This is mainly due to the non-uniform phase distribution or linear gradient developed by the magnetic susceptibility within a voxel, which in turn reduces the signal intensity; e.g., spin phases are dephased and thereby cancel each other resulting in a reduced signal. In this paper, a new concept for manipulating the susceptibility effect through the use of tailored RF pulses is proposed. As potential applications of the method, two different types of tailored RF pulses are introduced: one for susceptibility artifact correction and the other for contrast enhancement. The latter, for example, can be applied to angiography utilizing the paramagnetic property of deoxygenated blood. Both a theoretical study of the method and experimental results are reported.

Keywords