NMR Spectrum Analysis of Plasma Lipoprotein Lipid

혈장 lipoprotein lipid의 NMR spectrum 분석 - 메틸기 및 메털렌기의 line width에 의한 악성 종양 진단 -

  • Song, I.C. (Dept. of Biomed. Eng., Seoul National Univ.) ;
  • Min, B.G. (Dept. of Biomed. Eng., Seoul National Univ.)
  • 송인찬 (서울대학교 의과대학 의공학교실) ;
  • 민병구 (서울대학교 의과대학 의공학교실)
  • Published : 1987.07.03

Abstract

NMR spectrum analysis is performed to obtain the preliminary data for cancer detection. As NMR spectrum of plasma is dominated by the resonances of water, the resonances of plasma lipoprotein lipid is obscured by the water resonance. Thus, we can obtain the signal of plasma lipoprotein lipid using Ultracentrifugation. we analyzed the spectrum measuring the mean line widths of the methyl and methylene resonances for normal control group. As a result, the line width was Hz To obtain a potentially valuable approach to the detection of cancer, the performance of additional clinical trials in larger populations will be made.

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