고려인삼학회:학술대회논문집 (Proceedings of the Ginseng society Conference)
- 고려인삼학회 1980년도 학술대회지
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- Pages.131-135
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- 1980
EFFECT OF PANAX GINSENG ON XANTHINE OXIDASE ACTIVITY IN ETHANOL-INDUCED HYPERURICEMIA
- Huh Keun (Department of Pharmacology, College of Pharmacy Yeungnam University) ;
- Choi Chong Won (Department of Pharmacology, College of Pharmacy Yeungnam University)
- 발행 : 1980.09.01
초록
The influence of Panax ginseng on alcohol-induced hyperuricemia were observed. Changes of uric acid blood levels and hepatic xanthine oxidase activities were studied by means of treating alcohol intoxication with ginseng. It was found that a single dose (4 mg/Kg) of ginseng saponin administered intraperitoneally significantly inhibits the hepatic xanthine oxidase activities and decrease urate blood levels in ethanol-induced hyperuricemic mice. It was also observed that there were some difference in pharmacological aspect between Panax ginseng and allopurinol which is a potent inhibitor of xanthine oxidase from any sources.
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