Journal of Microbiology and Biotechnology

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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A New Analog of Antimycin from Streptomyces sp. M03033

  • Seo, Young-Wan (Marine Natural Products Laboratory, Korea Ocean research and Development Institute) ;
  • Cho, Ki-Woong (Marine Natural Products Laboratory, Korea Ocean research and Development Institute) ;
  • Rho, Jung-Rae (Marine Natural Products Laboratory, Korea Ocean research and Development Institute) ;
  • Mo, Sang-Jun (Marine Natural Products Laboratory, Korea Ocean research and Development Institute) ;
  • Shin, Jong-Heon (Marine Natural Products Laboratory, Korea Ocean research and Development Institute)
  • Published : 2001.08.01
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Abstract

A new secondary metabolite was isolated from the culture broth and mycelium of Streptomyces sp. collected from marine sediment. The structure of this compound was determined to be N-formylantimycic acid methyl ester, an acyclic derivative of antimycin, on the basis of combined chemical and spectral methods. The structure-activity relationship of antimycins is discussed.

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References

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