Evaluation of Subtractive Clustering based Adaptive Neuro-Fuzzy Inference System with Fuzzy C-Means based ANFIS System in Diagnosis of Alzheimer

Kour, Haneet;Manhas, Jatinder;Sharma, Vinod

  • Received : 2019.04.30
  • Accepted : 2019.05.26
  • Published : 2019.06.30


Machine learning techniques have been applied in almost all the domains of human life to aid and enhance the problem solving capabilities of the system. The field of medical science has improved to a greater extent with the advent and application of these techniques. Efficient expert systems using various soft computing techniques like artificial neural network, Fuzzy Logic, Genetic algorithm, Hybrid system, etc. are being developed to equip medical practitioner with better and effective diagnosing capabilities. In this paper, a comparative study to evaluate the predictive performance of subtractive clustering based ANFIS hybrid system (SCANFIS) with Fuzzy C-Means (FCM) based ANFIS system (FCMANFIS) for Alzheimer disease (AD) has been taken. To evaluate the performance of these two systems, three parameters i.e. root mean square error (RMSE), prediction accuracy and precision are implemented. Experimental results demonstrated that the FCMANFIS model produce better results when compared to SCANFIS model in predictive analysis of Alzheimer disease (AD).


AD;ANFIS;Fuzzy C-Means;Subtractive Clustering